Brain Stimulation for Basal Ganglia Disorders

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چکیده

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Brain Stimulation for Basal Ganglia Disorders

The basal ganglia (BG) have long been considered a purely motor region of the brain. However, over the last couple of decades it has progressively become clear that BG are central components of different cortical-subcortical circuits, described on a basic level as ‘motor’, ‘oculomotor’, ‘associative’ and ‘limbic’, according to the function of the cortical regions involved [1]. In turn, each cir...

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Physiology of basal ganglia disorders: an overview.

The pathophysiology of the movement disorders arising from basal ganglia disorders has been uncertain, in part because of a lack of a good theory of how the basal ganglia contribute to normal voluntary movement. An hypothesis for basal ganglia function is proposed here based on recent advances in anatomy and physiology. Briefly, the model proposes that the purpose of the basal ganglia circuits ...

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The Behavioural Neurology of Basal Ganglia Disorders

Basal ganglia disorders are common clinical conditions characterised by specific motor dysfunction and associated behavioral problems. The underlying pathophysiology primarily consists in alterations of the cortico-striato-thalamo-cortical pathways, which can be related to both neurodegenerative pathology (e.g. Parkinson disease, Huntington disease) and neurodevelopmental processes (e.g. Touret...

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Stimulation-induced dyskinesias inform basal ganglia models and the mechanisms of deep brain stimulation.

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The last two decades have witnessed an increasing interest in the use of computational modeling and mathematical analysis as tools to unravel the complex neural mechanisms and computational algorithms underlying the function of the basal ganglia and related structures under normal and neurological conditions (1–3). Computational modeling of basal ganglia disorders has until recently been focuse...

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ژورنال

عنوان ژورنال: Journal of Spine & Neurosurgery

سال: 2012

ISSN: 2325-9701

DOI: 10.4172/2325-9701.1000e102